I have no idea I don’t know
I believe the answer is: activation of large nerve fibers in your spinal cord
Gate control theory was popularized by Ronald Melzack and Patrick Wall, it views that non-painful area input closes the doors or "gates" to the painful area input, this exist in order to prevents pain sensation from coming through the central nervous system and being transferred across our body.
Costs/Socioeconomic status: Many areas have medicine and treatments that are expensive and unaffordable for average citizens. Those in poverty or simply below a specific wage level tend to risk going into more debt with ongoing treatments.
Lack of research and communication: A prime example would be the LGBTQ+ community. With a lack of communication and discrimination towards LGBTQ’s, it is harder to disclose important information and connecting certain diseases to specific groups of people.