1. Simple squamous epithelium
The cells are flat and only one layer.
2. Simple cuboidal epithelium
The cells are cuboid and only one layer.
3. Simple columnar epithelium.
The cells are columnar and only one layer.
4. Stratified squamous epithelium
The cells are flat and containing several layers.
5. Stratified cuboidal epithelium
The cells are cuboid and containing several layers.
6. Stratified columnar layer
The cella are columnar and containing several layers.
Answer:
Niche
Explanation:
Niche refers to adaptive features of an organism, its activity pattern and consumption of resources in the system.
Niche of an organism refers to its habitat, activity role and functional position within system. It includes the resources such as food that it obtains from the habitat for its survival.
Classifying things by observation can best be done by using a : Taxon
Taxon divided organisms into different groups based on their unique similarities, which is the best way to classify things if you're doing it by observation.
Human monoclonal antibody (mAbs) are emerging in the field of cancer therapy and have become an increasing proportion of new drugs that are recently approved. Although there are some methods to obtain antigen-specific mAbs from human B cells, it is generally impossible to directly immunize human beings with antigens of interest. For example, for infectious agents, those approaches are largely restricted. To solve these obstacles, two main approaches have been developed; either by humanizing antigen-specific antibodies from small experimental animals (which is laborious due to the great genetic differences from humans) or rely on the in vitro selection of antigen-specific binders from human antibody repertoires. However, the human mAbs developed by these methods are usually with low affinity.
We are now coming up with a much better idea that is humanizing non-human primates mAbs instead of murine mAbs. Due to the close genetic relationship with humans, immunized NHPs have more potential to be isolated with high affinity antibody to human target than other experimental species, such as mouse, rat and rabbit. In addition, with appropriate method, NHP antibodies are much<span> easier to be humanized</span> without any loss of affinity compared to widely used murine antibodies.
Resource: http://www.creative-biolabs.com/High-Affi-TM-Human-Antibody-Discovery.html
Answer:
Methotrexate inhibits the synthesis of DNA, RNA, and protein synthesis of the cells in the experiment.
Explanation:
Methotrexate competitively inhibits the enzyme dihydrofolate reductase (DHFR) which is involved in the synthesis of tetrahydrofolate from the inactive dihydrofolate. The methotrexate blocks the enzyme by binding to its active site thereby preventing further reaction of the dihydrofolate reductase enzyme and dihydrofolate. Tetrahydrofolate is a useful material for the de novo synthesis of thymidine, a nucleoside. And without thymidine, DNA synthesis is hindered. Methotrexate therefore inhibits the synthesis of DNA, RNA, thymidylates and of course protein synthesis.
