Which type of mutation causes sickle cell anemia

Biology

2 answers:

Licemer1 [7]3 years ago

7 0

It's a mutation of the gene that makes hemoglobin, and causes lots of pain and sickness.
Hope this helps!

IceJOKER [234]3 years ago

4 0

Sickle cell anemia is an inherited form of anemia, a disease that is characterized by inadequate healthy red blood cells to transport an adequate level of oxygen throughout the body.

Normally, red blood cells are flexible and round, and move easily through the blood vessels. In sickle cell anemia, red blood cells become stiff and sticky, and they are sickle-shaped or crescent-shaped. These irregularly shaped cells can get stuck in small blood vessels, which can slow or block the flow of blood and oxygen to different parts of the body.

This disease occurs due to mutations in the HBB gene, located on the short arm of chromosome 11, which encodes the beta-globin protein. This beta-globin is a subunit of hemoglobin which is found in blood erythrocytes.

Hemoglobin allows red blood cells to carry oxygen from the lungs to the entire body. In sickle cell anemia, abnormal hemoglobin causes red blood cells to become stiff, stocky and deformed.

You might be interested in

Primary targets for insulin action include all of the following except

Cloud [144]

Answer:

renal glucose reabsorption

Explanation:

4 0

3 years ago

What clues could you use to help determine whether movement of oslutes through the apicl and basolateral cell membranes is passi

Setler79 [48]

Answer:

Clues that can be used to determine whether the movement of solutes through the membrane is passive or active could be the molecule size, membrane potential, and the presence/absence of membrane protein.

Explanation:

Solutes transport through the cellular membrane depends on the solute size, membrane potential, and the presence/absence of integral membrane protein.

There are two types of transport: Active and passive.

- Passive transport: It does not need energy; it is driven by a chemical potential gradient. Small molecules with no charge are transported through the membrane in a gradient favor, from a high concentration region to a low concentration region. There are two types of passive transport: By simple diffusion (small molecules pass through the membrane by themselves) and by facilitated diffusion (molecules are helped by integral membrane proteins to pass through the membrane). In facilitated diffusion, the helping protein can be a channel protein (hydrophilic pores that allow the molecule to pass with no interaction) or a carrier protein (proteins with mobile parts that suffer modification as the molecule pass to the other side).

- Active transport: It does need ATP energy to pass the molecule through the membrane, as they have to move against the electrochemical gradient. This kind of transport is always mediated by a carrier protein. These proteins join with the molecules and suffer changes as they pass the solute to the other side of the membrane. An important example of this kind of transport is the sodium-potassium bomb.

6 0

3 years ago

The MN blood group in humans is under the control of a pair of co-dominant alleles, M (we will call the frequency of M, p) and N

KiRa [710]

Answer:

do you know some people have golden blood

6 0

3 years ago

Explain how living in a group, like these lions, increases the fitness of a species.

AysviL [449]

Explanation: Rivalry

There is safety in numbers, and with that, they can run together more often without the fear of being attacked, and must push themselves to match others, therefor getting fit

8 0

2 years ago

Which of these describes a quantitative observation?

shutvik [7]

The correct answer would be D) An observation that has a number associated with it.

7 0

3 years ago