Question

Why does a proteins 3D structure determine its biological function?

Answer 1

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your answer to this response is

Proteins are the most versatile macro molecules in living systems and serve crucial functions in essentially all biological processes. The proteins they  fold up into three dimensional structures that are determined by the sequence of amino acids in the protein polymer.

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FaithRawlins14

Answer 2

Our understanding of life at the molecular level is highly dependent on the ability to map the molecular details of individual proteins and nucleic acids as well as their interactions with each other and with small molecules (inhibitors, cofactors, substrates, etc.). The determination of 3-D structures of proteins is crucial for the understanding of these interactions as well as their structure–function relationships, which also has many practical applications in drug design and protein engineering.

https://www.creative-biostructure.com/protein-crystallization-and-structure-determination_13.htm