I believe it's B. BRCA1 and BRCA2.
Phat1 = 9/142
Phat 2 = 5/268
Phat 3 14/410
Test statistics = (Phat 1 - Phat 2) / (Square root of (phat × (1- phat))
times the square root of (1/n1 + 1/n2))
Test statistics = 2.373
P- value = 2× (1- normal cdf (2.373, 0, 1))
= 0.0176
At the level of significance, there is difference between the proportion of drug-resistant wihtin the two states.
C. Gradual
Hope this helps!
