An example of a missense mutation in a protein-encoding gene would most likely be a neutral mutation is option B: replacement of a polar amino acid with another polar amino acid at the protein's surface.
A frequent and well-known example of a missense mutation is the blood condition sickle-cell anemia. Missense mutations exist in the DNA at a single location in sickle-cell anemia patients. A different amino acid is required in this missense mutation, which also alters the overall structure of the protein. Similarly, replacement of a polar amino acid by another polar Ami no acid at the protein's surface is a missense mutation causing change in a single site.
A neutral mutation is one whose fixation is unrelated to natural selection. Therefore, the independence of a mutation's fixation from natural selection can be used to define the selective neutrality of a mutation.
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Complete question is:
Which example of a missense mutation in a protein-encoding gene would most likely be a neutral mutation?
a) Replacement of a polar amino acid with a nonpolar amino acid at the protein's outer surface
b) Replacement of a polar amino acid with another polar amino acid at the protein's surface
c) Replacement of a polar amino acid with another polar amino acid in the protein's interior
d) Replacement of a polar amino acid with a nonpolar amino acid in the protein's interior
Professional antigen-presenting cells, such as phagocytes, are the first cells to encounter a pathogen (apcs). This means they have the ability to activate cells of the adaptive immune system.
<h3>What is meant by Pathogen?</h3>
- A pathogen is an organism that infects its host with disease, and the severity of the disease symptoms is referred to as virulence.
- Pathogens include viruses, bacteria, unicellular and multicellular eukaryotes, and a wide range of other organisms.
- The bone marrow of an average healthy adult generates 100 billion new neutrophils per day. Because there are so many neutrophils in the body at any given time, they are often the first cells to reach the site of an infection.
- Long thought to be a component of the innate immune system, complement has recently emerged as an important regulator of the adaptive immune response.
Therefore the correct option is D) can activate cells of the adaptive immune system.
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Answer:
TRUE
Explanation:
Suspended silt diminishes the entrance of light into the water. This influences angle bolstering and tutoring hones and can lead to decreased survival.
DDT stands for dichloro-diphenyl-trichloroethane. The first kind of synthetic/artificial insecticides came into use in the 1940s. The earlier usage of DDT include: a) Killing of malarial vectors, b) Combatting Typhus and other insect borne human diseases, c) As a pest control in crops d) as a pest control in garden, live stock production and even at homes.
The negative impact of DDT could be felt for the first time when the pests that were earlier killed by use of DDT have now become pesticides resistant. In the 1950s in USA, the regulatory measures were adopted to reduce the usage of DDTs as its effects as a pesticides were no more long significant and also it was creating detrimental physical and psychological impacts on the human and environment.
It was in 1972 that the U.S. Environmental Protection Agency cancelled the order for banning the usage of DDT based on the adverse impact it produced on the environment, human and other life forms. Since then continuous studies are being conducted to analyse the impact of DDTs. In some later years it was established that DDT is the cause of producing tumors in liver.
Some of the common negative impacts produced by DDT as per the U.S. Department of Agriculture :
a) The non destructive nature – DDT can not be destroyed and thus it remains persistent in the atmosphere
b) It attacks the tissues of living organisms especially the animals and humans ( fatty tissue)
c) It can penetrate the atmosphere to deeper extent.
Now as per the current stuation, The use of DDT is controlled and other alternatives of pest control organisms is being deduced. As per the treaty of Stockholm Convention on POPs (Persistent organic pollutants) , usage of DDT for malarial control is justified but it puts a restrictive use of DDT as pesticides in other areas.
