Arrange the events of gene conversion of wild-type allele r to mutant allele r during meiotic recombination.

1 answer:

5 0

I found the whole exercise on the internet. Here are the events mentioned:
"-<span>Mismatched bases in the heteroduplex trigger mismatch repair.
-Gaps in the R (wild-type) allele sequence are filled by copying the r (mutant) allele.
-A heteroduplex is formed between </span>R (wild-type) and r (mutant) alleles.
-Mismatched bases are excised from the R (wild-type) allele.
-The wild-type R allele is converted to the mutant r allele."

The correct order is:
1. Gaps in the R (wild-type) allele sequence are filled by copying the r (mutant) allele.
2. A heteroduplex is formed between R (wild-type) and r (mutant) alleles.
3. Mismatched bases in the heteroduplex trigger mismatch repair.
4. Mismatched bases are excised from the R (wild-type) allele.
5. The wild-type R allele is converted to the mutant r allele.

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