Persistent chlorinated hydrocarbon pesticides persist in the environment and accumulate in the foods chain causing harmful effects on the environment including posing a threat to humans health in the long term. Nonpersistent organophosphate pesticides are more toxic than the former but degrade after a short life span. Therefore they cause immediate harm in case one is in contact with them.
The fact that they do not accumulate in the environment, they are more favourable than chlorinated hydrocarbon pesticides. Chlorinated hydrocarbon pesticides will affect several generations due to their accumulation in the environment. However they don't need to be re-applied hence are less expensive
Long-term potentiation (LTP) is considered a cellular correlate of learning and memory. The presence of G protein-activated inwardly rectifying K(+) (GIRK) channels near excitatory synapses on dendritic spines suggests their possible involvement in synaptic plasticity. However, whether activity-dependent regulation of channels affects excitatory synaptic plasticity is unknown. In a companion article we have reported activity-dependent regulation of GIRK channel density in cultured hippocampal neurons that requires activity oF receptors (NMDAR) and protein phosphatase-1 (PP1) and takes place within 15 min. In this study, we performed whole-cell recordings of cultured hippocampal neurons and found that NMDAR activation increases basal GIRK current and GIRK channel activation mediated by adenosine A(1) receptors, but not GABA(B) receptors. Given the similar involvement of NMDARs, adenosine receptors, and PP1 in depotentiation of LTP caused by low-frequency stimulation that immediately follows LTP-inducing high-frequency stimulation, we wondered whether NMDAR-induced increase in GIRK channel surface density and current may contribute to the molecular mechanisms underlying this specific depotentiation. Remarkably, GIRK2 null mutation or GIRK channel blockade abolishes depotentiation of LTP, demonstrating that GIRK channels are critical for depotentiation, one form of excitatory synaptic plasticity.
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Answer:
Waves interact with matter in several ways. The interactions occur when waves pass from one medium to another. Besides bouncing back like an echo, waves may bend or spread out when they strike a new medium. These three ways that waves may interact with matter are called reflection, refraction, and diffraction.
Explanation:
Answer:
Man's genotype: Bbdd
Woman's genotype: bbDd
First child's genotype: Bbdd
Second child's genotype: bbDd
Explanation:
This is a dihybrid cross involving two genes; one coding for eye color and the other for hair color in humans. The allele for brown eye (B) is dominant over the allele for blue eyes (b) in the first gene while the allele for dark hair (D) is dominant over the allele for red hair (d) in the second gene.
According to the question, A man with brown eyes and red hair will possibly possess genotypes: BBdd or Bbdd while a woman with blue eyes and dark hair will possibly have genotype: bbDD or bbDd. Considering the fact that they produced children with recessive traits for both gene (blue eyes and red hair), it means that they are heterozygous for their dominant trait. This means that the ideal genotype for the man is Bbdd since he will produce gametes containing B and b alleles for the first gene while the ideal genotype for the woman is bbDd since it will produce gametes with D and d allele for the second gene.
Hence, a child with brown eyes and red hair will possess genotype: Bbdd since he/she cannot receive two dominant alleles for the first gene from both parents. A child with blue eyes and dark hair will have genotype: bbDd since he/she cannot receive two dominant alleles of the second gene from both parents.
Answer:
Which statement explains what happens to older crust during seafloor spreading?
Explanation:
D. It moves away from a mid-ocean ridge.
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