Replication is performed prior to cell division
They concluded that horses evolved with the emergence of grasslands and an increase of predators. The digits of their early Eocene ancestor evolved into hooves.
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When we perform a study, we test a specific hypothesis to see whether our hypothesis is supported by the data or not. If our hypothesis is not supported by the data, then we can argue that a specific argument (that would be important for this hypothesis) does not have a claim in scientific research.
This is more broadly meant though. Usually you need to perform multiple studies and test multiple hypothesis to be able to critique a scientific argument and see whether the claims it makes and the predictions it makes hold up in scientific research.
