Answer:
Hepato- and nephrotoxicity of fluoride have been demonstrated in animals, but few studies have examined potential effects in humans. This population-based study examines the relationship between chronic low-level fluoride exposure and kidney and liver function among United States (U.S.) adolescents. This study aimed to evaluate whether greater fluoride exposure is associated with altered kidney and liver parameters among U.S. youth.
This cross-sectional study utilized data from the National Health and Nutrition Examination Survey (2013–2016). We analyzed data from 1983 and 1742 adolescents who had plasma and water fluoride measures respectively and did not have kidney disease. Fluoride was measured in plasma and household tap water. Kidney parameters included estimated glomerular filtration rate (calculated by the original Schwartz formula), serum uric acid, and the urinary albumin to creatinine ratio. Liver parameters were assessed in serum and included alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, blood urea nitrogen, gamma-glutamyl transferase, and albumin. Survey-weighted linear regression examined relationships between fluoride exposure and kidney and liver parameters after covariate adjustment. A Holm-Bonferroni correction accounted for multiple comparisons.
The average age of adolescents was 15.4 years. Median water and plasma fluoride concentrations were 0.48 mg/L and 0.33 μmol/L respectively. A 1 μmol/L increase in plasma fluoride was associated with a 10.36 mL/min/1.73 m2 lower estimated glomerular filtration rate (95% CI: −17.50, −3.22; p = 0.05), a 0.29 mg/dL higher serum uric acid concentration (95% CI: 0.09, 0.50; p = 0.05), and a 1.29 mg/dL lower blood urea nitrogen concentration (95%CI: −1.87, −0.70; p < 0.001). A 1 mg/L increase in water fluoride was associated with a 0.93 mg/dL lower blood urea nitrogen concentration (95% CI: −1.44, −0.42; p = 0.007).
Fluoride exposure may contribute to complex changes in kidney and liver related parameters among U.S. adolescents. As the study is cross-sectional, reverse causality cannot be ruled out; therefore, altered kidney and/or liver function may impact bodily fluoride absorption and metabolic processes.
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The answer to this one is the first one
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❖ B. Punnet Square is a chart used to show the possible outcomes of allele combinations that parents can pass on to their offspring.
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<u>Answer:</u>
Q: Which skeletal system <u>disorder</u> might she be suffering from?
A: <u>Osteoporosis</u>
Q: What <u>techniques</u> could be used to diagnose her condition?
A: <u>Bone mineral density (BMD) test</u> or <u>dual energy X-ray absorptiometry (DXA) scan</u>
Q: What treatments are available?
A: Medication, healthy food.
<u>Explanation:</u>
<u>The vertebral discs between vertebrae could shrink with age</u>. Therefore, a height loss up to 1-inch is normal. However, if the height loss is more then it is possibly due to <u>osteoporosis</u>.
A <u>bone mineral density test</u>, also known as <u>dual energy X-ray absorptiometry</u> scan, is a well-adapted test to measure the amount of calcium and other minerals in the bones. It uses <u>X-rays</u> to measure the content of calcium and thus strength of bones.
A person who is already suffering from osteoporosis should be treated with <u>medicine</u> right away so that it <u>stops</u> further <u>deterioration of the bones</u> and <u>avoid any future bone fractures</u>. Further, it can be handled by <u>eating a healthy diet</u> and <u>supplements</u> such as <u>vitamins D</u>. In case some of the bones/vertebrae are <u>already fractured</u>, <u>surgical approaches</u> might be necessary.
Answer:
C.
Explanation:
Absolute dating is defined as the method used to determine the age of biotic or abiotic things on a specified chronology in geology and archaeology.
Layers of the soil are used to determine the age of a geologic event is not a form of absolute dating because the deepest river deposits in the specific basin is used to determine the geological event.
So, the deposits of soil are used to tell the the age of a geologic event and not the layers of soil.
Hence, the correct option is C.