If there can be only one 1 and only one 2, the remaining digits must all be 0. The digits 1 and 2 can be anywhere in the 8 digits, and can be in either order.
There are 8 possible locations in the sequence for the 1, then 7 possible locations for the 2. The total number of possibilities is 8·7 = 56.
You can multiply by 12 because to get rid of the fractions all terms should be divided by the LCM (ie the smallest multiple that is exactly divisible by 2, 4 and 3)
Multiples of 3 = 3, 6, 9, 12
Multiples of 4 = 4, 8, 12, 16
Multiples of 2 = 2, 4, 6, 8, 10, 12
Therefore the fractions should be multiplied by 12