The duplication of homeotic ( H o x ) genes has been significant in the evolution of animals because it <u>permitted </u><u>the </u><u>evolution </u><u>of novel forms</u>
<h3>What is the Hox genes and evolution?</h3>
Hox proteins are a family of transcription factors that have undergone extensive conservation. They were first identified in Drosophila for their crucial functions in regulating segmental identity along the antero-posterior (AP) axis.
The regionalization of the AP axis and changes in the expression patterns of these genes have been strongly correlated during the past 30 years across a wide range of evolutionarily distinct species, indicating that Hox genes have been essential in the evolution of new body plans within Bilateria.
Despite this extensive functional conservation and the significance of these genes for AP patterning, many important concerns about Hox biology remain.
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