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cAMP in the cytoplasm
Many cAMP can be generated as a second messenger to amplify the signal in response to hormone binding.
Answer:
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Rutherford overturned Thomson's model in 1911 with his well-known gold foil experiment in which he demonstrated that the atom has a tiny and heavy nucleus. Rutherford designed an experiment to use the alpha particles emitted by a radioactive element as probes to the unseen world of atomic structure.