* More than 40 proteins and glycoproteins involved in the complement system are synthesized by the liver, macrophages, epithelial cells, they are present in the blood in plasmatic form, membrane, some have an enzymatic activity, regulator or membrane receptorThese are elements of the humoral innate immune response, they fight infections, purify immune complexes and apoptotic bodies.
<span>There are indeed three ways to activate the complement:</span>
Classical pathway: Activated by Immunoglobulins in immune complexes, aggregated Immunoglobulins, DNA, CRP, apoptotic bodies .......it involves nine fractions, starting with C1, then C4, C2, C3, to form a classical C5 convertase, then, activation of C5, C6, C7, C8, C9.
Alternative pathway: activated by polysaccharides (bacterial endotoxin), vascular wall poor in sialic acid, aggregated IgE ...C3b like is the first component in the alternate channel cascade, it will create an amplification loop, and form an alternative C5 convertase.
Lecithin pathway: Activated by mannose, fucose (carbohydrate of microorganisms)The first component is the complex MBL / MASP1 / MASP2: "mannose-binding protein": works according to the same principle as the complex C1 of the classical way (MASP2 cleaves the C4 and the rest of the cascade is equivalent to that of the classical way).
the three ways have the same outcome: A C5 convertase (formed by one of the pathways) cleaves C5 into C5a and C5b: C5b is deposited far from other fractions on the antigenic surface. The fixation of C5b in the cell is followed by that of C6, C7, C8, and C9 (9 molecules of C9): formation of the membrane attack complex (MAC) ==> Death of the cell by osmotic shock
Answer:
Your body will always try to keep you at the same temperature, for example, even when it's raining. Asthma is a good example of homeostasis gone wrong and the body acts out of proportion to a stimulus starting a process that leads to symptoms.
OPTIONS:
a) Blood delivers calcium and phosphate ions that are needed for building bone extracellular matrix.
b) Blood carries carbon dioxide to body tissues and removes oxygen for use by other organs.
c) Blood carries newly absorbed nutrients and water to the liver.
d) Blood circulates cells and chemicals that carry out immune functions.
e) Blood delivers clotting factors and WBCs that aid in hemostasis when skin is damaged
Answer:
b) Blood carries carbon dioxide to body tissues and removes oxygen for use by other organs.
Explanation:
Options a, c, d, e are all true statements about the contributions of the cardiovascular system to other body systems except option b which states that “Blood carries carbon dioxide to body tissues and removes oxygen for use by other organs”.
Actually, the cardiovascular system works together with the respiratory system to supply oxygen to body tissues as blood is circulated in the body, while carbon dioxide is removed from the body at the lungs. <em>In order words, carbon dioxide is removed, while oxygen is picked up as blood is transported through the capillaries of the lungs.
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Answer:
B replication
Explanation:
the teacher demonstrated, so the students were told to CARRY OUT THE *same* experiment, AKA REPLICATION >:3
Answer;
As liquid water freezes, the molecules arrange themselves in a way that takes up more space than liquid water. What would most likely occur if the arrangement of frozen water molecules required less space than that of liquid water molecules? A).The density of ice would be greater than the density of liquid water, and ice would not float. B). Ice would form in layers, and liquid water would get trapped in between the layers. Liquid water would have a higher specific heat, making it less likely to undergo vaporization. C).The freezing point of water would decrease, making ice more difficult to form.
