Question

Why do charged molecules have difficulty crossing a phospholipid bilayer?

Answer 1

The answer to this question would be because phospholipid is polar has a charge.

Since phospholipid is polar, it can attract molecule with a charge. That will cause the molecule cant move easily pass the membrane. The hydrophobic molecule doesn't have charge, so the molecule can pass through the phospholipid membrane if it small enough.

Answer 2

Most polar atoms have low solvency in the hydrocarbon center of a phospholipid bilayer and, as a result, have low penetrability coefficients over the bilayer.

Further explanation

Phospholipid bilayer

The lipid bilayer (or phospholipid bilayer) is a polar membrane made up of two layers of lipid particles. The cell membrane of practically all life forms and numerous infections are made of a lipid bilayer, just like the nuclear layer encompassing the nucleus, and different layers encompassing sub-cell structures. The lipid bilayer is the obstruction that keep particles, proteins and different atoms where they are required and keeps them from diffusing into regions where they ought not be. Lipid bilayers are in a perfect world fit to this job, despite the fact that they are just a couple of nanometers in width, they are impermeable to most water-solvent (hydrophilic) particles. Bilayers are especially impermeable to particles, which enables cells to control salt fixations and pH by shipping particles over their films utilizing proteins called particle pumps.

Polar molecules

Such molecules which have electric charge, they have negative charge on one side and positive charge on another side. Water is an example of polar molecule.

Non-Polar molecules

Such molecules which have electric charge are known as non-polar molecules. For example, Benzene - C6H6.

Why polar molecule face difficulty to cross lipid bilayer?

The layer is profoundly porous to non-polar (fat-dissolvable) molecules. The penetrability of the layer to polar (water solvent) particles is exceptionally low, and the porousness is especially low to large size polar molecules.

Answer details

Subject: Biology

Level: High school

Key words

• Phospholipid bilayer
• Polar molecules
• Non-polar molecules
• Why polar molecule face difficulty to cross lipid bilayer?

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