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bulgar [2K]
3 years ago
6

How are cancer therapies tailored to nucleotide synthesis -explain using the example of fluorouracil and methotrexate.

Biology
1 answer:
nika2105 [10]3 years ago
3 0

Answer:

By preventing the synthesis of DNA halting cell growth.

Explanation:

Fluorouracil and methotraxate prevent the synthesis of the neucleoside Thymidine thus preventing DNA replication and elongation. Methotraxate has a structure analogous to Folic acid which is important for thymidine synthesis. Thus, it acts as a competitive inhibitor on dihdrofolate reductase an enzyme that is essential for tetrahydrofolate formation, a folic acid derivative.

Fluorouracil acts by inhibiting thymidylate synthase which catalyses an essential step in Thymidine synthesis.

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1. breeding of individuals that have genes for two different characteristics dihybrid cross 2. a grid system used to predict pos
icang [17]
1. breeding of individuals that have genes for two different characteristics:
DIHYBRID CROSS.
We call it a dihybrid cross when we are considering a cross between two different traits.
"di" means having two traits involved (for example, trait A and trait B), the "hybrid" means that each trait will have two different alleles (for gene A: A or a; for gene B: B or b), one is dominant and the other is recessive.

2. a grid system used to predict possible combinations of genes due to random fertilization: PUNNETT SQUARE
The Punnett square is a grid system that helps us predict an outcome of a cross or a breeding experiment. We this, we can determine the probability of an offspring having a particular genotype.
This is very useful when we are considering more than one gene,  making it less confusing.

3. a condition in which both alleles are dominant: CODOMINANCE
Tere are alleles that have the capacity of dominating at the same time, and when an organism is heterozygotic, both alleles are expressed.
For example, a white chicken(WW) crossed with a black chicken (BB):  100% of the offspring being WB. With this genotype, they have black feathers and white feathers. It's not a blend of colors, but a case where both are expressing.

4. when more than two alternatives exist for a gene: MULTIPLE ALLELES
Mendel thought that only two possible alternatives could exist for a gene, but there are cases that have more than 3 possibilities. Some of those can be really popular in a population while others not so much.
This happens with rabbit's fur. They can be black, brown, grayish,
Himalayan patterning or white fur.

 5.a condition in which neither pair of alleles is dominant or recessive, so the traits blend in the phenotype: INCOMPLETE DOMINANCE
Some alleles are not completely dominant, and when that's the case the phenotype of a heterozygous organism will be a mix between the phenotypes of its homozygous parents.
For example:
plant 1: RR -red
plant 2: rr-white
By crossing this plants we will obtain 100%  of the offspring with a color mix: pink.(genotype: Rr)
Red and white are not completely dominating so it results in a blend of colors.


3 0
3 years ago
1. Which of the following statements are true?
hammer [34]

Your answers would be:

1. ---- B. A cell cannot be subdivided into smaller units that maintain the living state.

2. ---- The organism is a eukaryote because it has a nucleus.

3. ---- D. Water would flow into them because they are hypertonic to external environment.

If you want to know why:

1. The cell is the basic unit of life or in other words, its the smallest unit that makes up a living thing. It does not subdivided further if you are talking about sustaining life. Yes, it is made up of smaller units of organelles, but these organelles work together as a single unit (as a cell), to do life sustaining processes.

2. The organism is a eukaryote because of the presence of a nucleus. This is one of the main features of a eukaryote that differentiates it from a prokaryote. Prokaryotes to not have a true nucleus.

3. Water would flow into them, causing the cell to swell and eventually burst if the concentration of solutes would not even out before then. The process of osmosis is what brings the water into the cell. The cell would have a higher solute concentration than freshwater. Through osmosis, the water would then go to the area of higher concentration, which would be the cell.


3 0
3 years ago
Read 2 more answers
PLS HELP I WILL GIVE YOU BRAINLIEST AND PLS EXPLAIN YOUR ANSWER!!!
Kipish [7]

Answer:

Most likely centripetal force. Newton's first law states that an object in motion will continue to remain in motion unless acted upon by an outside force. In this case, that outside force is the centripetal force.

Explanation:

Hope this helps :)

8 0
2 years ago
A fungus that is a parasite might feed on a _____.
11Alexandr11 [23.1K]
The answer would be "a person's skin"

hope this helps :)
5 0
2 years ago
This is wrong its dna
weqwewe [10]
?????? What's even the question?
8 0
3 years ago
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