The nurse can give the client antidepressants such Duloxetine. Even though one is not depressed, one can still take this as this can also alleviate pain. Another medication the client can take is an anti seizure medication. An example of this is Pregabalin. It would prevent nerves from sending pain signals to the brain thus can also help ease the pain of a person suffering from Fibromyalgia.
Answer: Option B
The enzyme has changed shape because of high temperature.
Explanation:
Enzymes are biological catalysts in living organisms that speed up the rate of chemical reactions.
High temperature changes the shape of enzymes.
Increase or high temperature lead to decrease in enzymes activities. This is due to enzyme protein been denatures by high temperature which is the breaking of molecular bonds within the enzyme protein. When the enzymes bonds are broken, the shape of the enzymes changes and they no longer act as catalysts.
Striated muscles contain repeating sarcomeres of overlapping arrays of long, thin actin and thicker myosin filaments. Myosin filaments contains the myosin heads, which are enzymes that can bind to actin, split and make use of the energy from ATP. When muscle contraction starts, myosin heads bind to actin, change their configuration on actin, liberating the products of ATP hydrolysis and causing slide of the actin and myosin filaments. The action of the proteins troponin and tropomyosin on the actin filaments regulates vertebrae striated muscle contraction. The release of calcium ions from the sarcoplasmic reticulum is triggered by the nervous stimulation which causes depolarization of muscle membrane. Calcium ions bind to troponin and thus cause or allow the tropomyosin strands on the actin filament to move so that the part of the actin surface where myosin heads need to bind is uncovered. Contraction then occurs and only stops when the sarcoplasmic reticulum pumps calcium out of the muscle interior.
So basically, what triggers the uncovering of the myosin binding site on actin is the calcium ions binding to troponin and changing configuration.
