Because it is easily accessible and has a mild immune response, the retina makes a good target for gene therapy.
- In a mouse model, the inner retina was highly effectively transduced by an intravitreally injected adeno-associated virus (AAV) vector.
- The vitreous and internal limiting membrane (ILM) operated as obstacles to transduction in large animals, reducing the efficacy of retinal transduction.
- Before administering AAV vectors, we performed vitrectomy (VIT) and ILM peeling on cynomolgus monkeys to get around these obstacles.
- The findings suggest that surgical ILM peeling prior to AAV vector delivery would be beneficial for retinal disease treatment and safe for effective transduction of the nonhuman primate retina.
Learn more about the adeno-associated virus (AAV) with the help of the given link:
brainly.com/question/28205495
#SPJ4
Answer:
You need to add the graph or a picture we cant just answer this for you if it doesnt have something to show us a graph when needed.
Explanation:
<span>Your answer would be inadequate sunlight.</span>
Answer:
Cuando el entorno donde se encuentra la semilla cuenta con las condiciones idóneas se produce el inicio de la vida de la nueva planta. El proceso comienza con la ruptura del envoltorio de la semilla y la aparición de la raíz. De manera sencilla podemos dividir este hecho en varias etapas que son clave para comprender el proceso de crecimiento de las plantas. Así es cómo crecen las plantas.
Explanation: