Viruses are at the heart of this century-old debate. Viruses<span> are parasites that infect plants, animals, fungi and bacteria. They consist of genetic material surrounded by a protein coat and are unable to grow or reproduce without a host. The classification of viruses has confused scientists for nearly 100 years. Originally they were viewed as poisons. In fact, the word ''virus'' is Latin for ''poison.'' They have since been viewed as living creatures, then mere bio-chemical compounds, and, most recently, somewhere in between chemical compounds and lifeforms.</span>Non-cellular life<span> refers to organisms, such as viruses, that exist without any cells, and it is a very controversial topic. The cell theory, which is one of the fundamental tenets of biology, states that all living things are composed of cells and that cells are the basic units of life. So the idea that something can be considered alive without having cells is an issue that is up for debate.
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Answer:
The positive charge of the histone proteins get reduced due to the process of histone acetylation, thus making the wrapping of DNA around the histones less tightened. The loose connected DNA afterward associates with the transcription factors for the articulation of the genes situated in that area.
Generally, when there is no requirement of gene anymore, the acetyl groups from the histones get withdrawn by the activity of histone deacetylase enzyme (HDAC9) that makes the DNA tightly wrapped and inaccessible again. In case, when less expression of histone deacetylase enzyme occurs, the process of deacetylation fails to take place. This indicates that within an immune cell, at the time of infection, the inflammatory gene, which was made available does not get re-wrapped firmly around the histones.
