1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
Ann [662]
3 years ago
15

Define the 3 signals for activation and the 3 outcomes of the complement system.\

Biology
1 answer:
sp2606 [1]3 years ago
8 0
* More than 40 proteins and glycoproteins involved in the complement system are synthesized by the liver, macrophages, epithelial cells, they are present in the blood in plasmatic form, membrane, some have an enzymatic activity, regulator or membrane receptorThese are elements of the humoral innate immune response, they fight infections, purify immune complexes and apoptotic bodies.
<span>There are indeed three ways to activate the complement:</span>
Classical pathway: Activated by Immunoglobulins in immune complexes, aggregated Immunoglobulins, DNA, CRP, apoptotic bodies .......it involves nine fractions, starting with C1, then C4, C2, C3, to form a classical C5 convertase, then, activation of C5, C6, C7, C8, C9.

Alternative pathway: activated by polysaccharides (bacterial endotoxin), vascular wall poor in sialic acid, aggregated IgE ...C3b like is the first component in the alternate channel cascade, it will create an amplification loop, and form an alternative C5 convertase.

Lecithin pathway: Activated by mannose, fucose (carbohydrate of microorganisms)The first component is the complex MBL / MASP1 / MASP2: "mannose-binding protein": works according to the same principle as the complex C1 of the classical way (MASP2 cleaves the C4 and the rest of the cascade is equivalent to that of the classical way).

the three ways have the same outcome: A C5 convertase (formed by one of the pathways) cleaves C5 into C5a and C5b: C5b is deposited far from other fractions on the antigenic surface. The fixation of C5b in the cell is followed by that of C6, C7, C8, and C9 (9 molecules of C9): formation of the membrane attack complex (MAC) ==> Death of the cell by osmotic shock
You might be interested in
Which of the following is not true of cells?
Mrac [35]
The last one
some cells are living and some cells are not

i think
7 0
3 years ago
Read 2 more answers
A scientist constructs a graph to show the age structure of the human population of Country Y. The graph is shown here.
creativ13 [48]
Theeee anssswwweeerrrr issss (C) forrrrr yourrrrr queessttiioooonnnn
4 0
2 years ago
Ribosomes attaches to the smooth ER make proteins? True or False
Pavlova-9 [17]
Answer:

True.

Explaination:

I’ve done this before.
7 0
3 years ago
Predict how results would change if the field were watered daily. A. Nothing would change. B. All the plants would increase in n
iragen [17]

Answer: B

Explanation:

I'm not sure, but I'd say that the best answer choice would be B because most of the plants would grow, and none would die off. The smaller plants would grow, and would grow in, and most if not all of the larger would just continue to grow, if they aren't already full grown.

Hope this helped!

6 0
3 years ago
How can two parents without hitchhiker's thumb have a child who does have hitchhiker's thumb
Naddik [55]
That Trait (Hitchhiker's thumb) may be recessive in both the parents but when they transmitted their genes to their offspring, it became dominant in that 'cause of two similar genes (Homozygous Condition).

Hope this helps!
6 0
2 years ago
Read 2 more answers
Other questions:
  • Which of the following organelles is important for lipid synthesis and detoxification of the cell?
    13·1 answer
  • Which is the result of an object's motion?.
    12·1 answer
  • Bacteria protect themselves from viruses by fragmenting viral dna upon entry with:
    7·1 answer
  • Is the information crisis in a cell solved by the replication of the DNA before the cell division?
    13·1 answer
  • Which of the following best describes the function of enzymes in biological systems?
    13·2 answers
  • I feel really really really d\/mb right now
    13·2 answers
  • Select the correct answer.
    5·1 answer
  • Fatty acids are catabolized through which process?.
    6·1 answer
  • What is zoology??? ?​
    10·1 answer
  • Research three branches of biology. for each branch of bilogy describe what is studies, what careers involve that branch and how
    5·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!