* More than 40 proteins and glycoproteins involved in the complement system are synthesized by the liver, macrophages, epithelial cells, they are present in the blood in plasmatic form, membrane, some have an enzymatic activity, regulator or membrane receptorThese are elements of the humoral innate immune response, they fight infections, purify immune complexes and apoptotic bodies. <span>There are indeed three ways to activate the complement:</span> Classical pathway: Activated by Immunoglobulins in immune complexes, aggregated Immunoglobulins, DNA, CRP, apoptotic bodies .......it involves nine fractions, starting with C1, then C4, C2, C3, to form a classical C5 convertase, then, activation of C5, C6, C7, C8, C9.
Alternative pathway: activated by polysaccharides (bacterial endotoxin), vascular wall poor in sialic acid, aggregated IgE ...C3b like is the first component in the alternate channel cascade, it will create an amplification loop, and form an alternative C5 convertase.
Lecithin pathway: Activated by mannose, fucose (carbohydrate of microorganisms)The first component is the complex MBL / MASP1 / MASP2: "mannose-binding protein": works according to the same principle as the complex C1 of the classical way (MASP2 cleaves the C4 and the rest of the cascade is equivalent to that of the classical way).
the three ways have the same outcome: A C5 convertase (formed by one of the pathways) cleaves C5 into C5a and C5b: C5b is deposited far from other fractions on the antigenic surface. The fixation of C5b in the cell is followed by that of C6, C7, C8, and C9 (9 molecules of C9): formation of the membrane attack complex (MAC) ==> Death of the cell by osmotic shock
If you are suffered to a broken nose the bones that are potentially involved are inferior nasal concha, lacrimal, vomer, and nasal bones.
A Broken nose is a fracture of nasal bones, because the nose has such a prominent and unprotected position in the center of the face. Boken nose significantly alters your appearance, it can also make it much harder to breathe through the nose.
The correct is B Hormones are chemical signals between cells transported in blood or hemolymph.
Explanation:
Hormones are called chemical messenger of the cell because they transmit chemical information from one cell to the target cell and regulating the functioning of that target cell by activating specific proteins related to the functioning of that target cell.
Hormone is secreted from its source gland such as Pituitarygland, thyroid gland,adrenal gland.After being secreted hormones are transported via the blood stream to the target cell and binds to receptor of that target cell thus allowing the target cell to exert its biological function.
Parents are encouraged to raise equal power relations among girls and boys. Here are three ways to parents in which they can improve <span>equal power relations: (1) in terms of the amount of food or the choice of food, let them have the freedom to choice what they want. Whatever wrong they do, they have to be consented. (2) Whatever problem they have, it's better for dads to talk to their sons, moms to their daughters. (3) If they are already grown-ups, let them decide what track or course they want to take. In that way, they will be able to exercise their freedom well. </span>