Do you want the catholic answer or do you just want a general answer, because it could be an opinion.
It would be an oncogene, these can be inherited mutations of proto-oncogenes that cause the oncogene.
Answer is Middle Paleozoic era.
Paleozoic era was in 542 Ma - 245 Ma and it has 6 periods as Cambrian, Ordovician, Silurian, Devonian, Carboniferous and Permian.
360-280 Ma - forming of vascular plants with woody tissues, seeds and veins.
430 - 410 Ma - forming of jawed fishes and first amphibians.
420 Ma - forming of scorpions
360 Ma - forming of crustaceans.
The answer is D, all of the above.