Answer: Higher temperatures disrupt the shape of the active site, which will reduce its activity, or prevent it from working. The enzyme will have been denatured . ... The enzyme, including its active site, will change shape and the substrate no longer fit. The rate of reaction will be affected, or the reaction will stop. So the answer is c i hope this helped:)
Explanation:
Others pinpoint 1637 as the true origin of Thanksgiving, owing to the fact Massachusetts colony governor John Winthrop declared a day of thanks-giving to celebrate colonial soldiers who had just slaughtered 700 Pequot men, women, and children in what is now Mystic, Connecticut.