MAD (mitotic arrest deficient) are proteins related to spindle cell cycle checkpoint and it is important since they prevent the segregation of sister chromatids until all have bound to the spindle.
The cell cycle ensures the duplication of the genome and its distribution in daughter cells by passing through a coordinated and regulated sequence of events.
A series of checkpoints guarantee the orderly progression of the phases of cell division and the correct distribution of the duplicated genetic material in the daughter cells.
The checkpoints during mitosis are:
- At the end of stage G1 and before S.
- Before anaphase in mitosis.
- DNA damage checkpoints in G1, S or G2.
The checkpoint before anaphase in mitosis guarantees the separation of chromosomes, and operates by activating the Mad2 protein that prevents the degradation of segurin, until the conditions are appropriate.
That is, the Mad2 protein prevents the segregation of sister chromatids until they have all bound to the spindle.
Therefore, we can conclude that MAD (mitotic arrest deficient) are proteins related to spindle cell cycle checkpoint and it is important since they prevent the segregation of sister chromatids until all have bound to the spindle.
Learn more here: brainly.com/question/9790187
Answer:
A ‘receipt’ is a statement saying that what is presented is true
Explanation:
Hope this helps!（づ￣3￣）づ╭❤～
In the chart provided below, you can see that the first species belongs to the plant kingdom, and the other three belong to the animal kingdom. The kingdom is a very high level of classification, right below the level of domains. Therefore, organisms that belong to different kingdoms are very distantly related.
Answer:
interphase and the mitotic (M) phase.
Explanation:
The stages of the cell cycle are divided into two major phases: interphase and the mitotic (M) phase.
Answer:
The answer is Vitamin E or α-tocopherol.
Explanation:
Vitamin E is a <u>fat-soluble</u> vitamin is first absorbed in the small intestine and is then <u>stored at the liver</u>. It is an <u>antioxidant</u> which <u>protects cells from free radicals or reactive oxygen species (ROS)</u>. It can also prevent bad cholesterol from depositing in the blood vessels.
Vitamin E can be <u>naturally found in nuts, seeds, and vegetable oils</u>. As a dietary supplement, it takes the form of α-tocopherol. The RDA depends on the age of the person, as it may range from <u>4 mg to 15 mg per day</u>.
<u>Vitamin E deficiency is so rare</u> that it will only occur if the person has a <u>fat malabsorption illness like Crohn's disease, abetalipoproteinemia</u>, etc. Symptoms of deficiency include <em>muscle weakness, retinal degradation, peripheral neuropathy, and an immunocompromised state</em>.
