An individual's self-esteem can be affected by genetics as well as environmental factors, and poor self-esteem often begins in childhood. A person who experiences an abusive childhood or who didn't get enough approval from authority figures, feels his or her self-worth was based on achievements or feels excluded will often have poor self-esteem.
Answer:both smoking weed when you are depressed because it will make you even more depressed trust me i know and also taking a presicption painkiller just for a high. Those are two examples of drug misuse.
I believe the answer is either B. or C.
Hope this helps!
The answer is true, you can use both