Answer:Smallpox and vaccination are intimately connected. Edward Jenner developed the first vaccine to prevent smallpox infections, and this success led to the global eradication of smallpox and the development of many more life-saving vaccines.
Explanation:
The newspaper design element which has changed drastically from 1900 to today is option C that is the advertisements moved from the last page to front page.
<h3>What is a newspaper?</h3>
A newspaper is a source to gather news of all over the world every day. It is a printed paper containing news, articles, advertisements, and correspondence.
In early 1900, newspaper does not consist much advertisement but till the time passed, now it is changed a lot. From having advertisements at the last page than to middle and then now at the front page it changed so excessively.
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Members of the ku klux Klan attacked African Americans
