In the human embryo, the first site of blood formation is the yolk sac. Later in embryonic life, the liver becomes the most important red blood cell-forming organ, but it is soon succeeded by the bone marrow, which in adult life is the only source of both red blood cells and the granulocytes. Their job is to transport oxygen to the body's tissues in exchange for carbon dioxide, which is carried to and eliminated by the lungs. Red blood cells are formed in the red bone marrow of bones. Stem cells in the red bone marrow called hemocytoblasts give rise to all of the formed elements in blood. Erythroid (red blood) cells are the first cell type to be specified in the postimplantation mammalian embryo and serve highly specialized, essential functions throughout gestation and postnatal life. The existence of 2 developmentally and morphologically distinct erythroid lineages, primitive (embryonic) and definitive (adult), was described for the mammalian embryo more than a century ago. Cells of the primitive erythroid lineage support the transition from rapidly growing embryo to fetus, whereas definitive erythrocytes function during the transition from fetal life to birth and continue to be crucial for a variety of normal physiologic processes. Over the past few years, it has become apparent that the ontogeny and maturation of these lineages are more complex than previously appreciated. In this review, we highlight some common and distinguishing features of the red blood cell lineages and summarize advances in our understanding of how these cells develop and differentiate throughout mammalian ontogeny.
Answer:
4
Explanation:
The offensive team gets 4 attempts to advance the ball ten yards in football.
If they fail to do so, they must surrender the ball to the opponent, usually by punting on the fourth down.
Answer:
SOAP AND WATER
Explanation: YOU WILL NEED TO CLEAN THE CUT
A nurse should first try to keep the surroundings at a comfortable temperature, and keep the feet dry, clean, and covered.
Explanation:
Prevention is the best treatment for diabetes patients as healing can take ages for them, especially sores on the toes and fingers. This increases the risk of amputation. Thus, a nurse should warm up and avoid damage to the feet.
Puberty, and there are many websites and books that offer information so you know what to expect.
