Answer: Combining a basic API with citric acid to produce the citrate salt of the API.
Explanation:
Chemical modifications refers to the processes that involve changes in the general composition of drugs to produce another entity with different chemical properties.
From the answer, Basic API combine with citric acid to produce the citrate salt of API which have different chemical properties from the reactants.
Answer:
3. An even number of chromosomes are required for synapsis during prophase I and proper pairing during metaphase
Explanation:
Mules are hybrids of a cross between a female horse and a male donkey. Horses contain 64 chromosomes while donkeys contain 63 chromosomes in their somatic cells respectively. This means that they each produce 32 and 31 chromosomes respectively during meiosis. A mule, hence, contains 32+31= 63 chromosomes in their somatic cells.
This chromosome number in mules are uneven for meiosis to occur because meiotic division requires that an even number of homologous chromosomes pair together in a process called SYNAPSIS during prophase I of meiosis I. This is impossible in a mule because of the uneven number of chromosomes in its cells.
Also, during metaphase of meiosis, the homologous chromosomes need to be properly aligned at the equator for separation to occur. This is also impossible in a mule considering the number of chromosomes that don't add up.
Due to this reason of unevenness in the number of chromosomes present in a mule, meiosis will not occur and if meiosis (gamete formation) does not occur, reproduction cannot take place. Therefore, the mule is a sterile species i.e. cannot produce offsprings via sexual reproduction.
The correct answer is - Most killer whales congregate in the areas that are near the Arctic/Antarctic Circles.
The killer whales have a very large distribution, and they can be found in all oceans, apart from the Southern Ocean. It is noted though that the population density of the killer whales differs from place to place. The higher concentrations are found around the Arctic and Antarctic Circles, where there's cool rich waters, while in the lower latitudes they are much rarer. The reason for this probably lies in the fact that most of the animals that are considered to be the prime food source of the killer whales are living in this rich cold waters.
Answer:
1. Hematoma is an open injury that occurs whenever a large blood vessel is damaged and bleeds rapidly. False
2. You should never remove an avulsion skin flap, regardless of its size. True
3. When possible, ALS providers should administer IV fluid within 3 minutes after the crushing object is lifted off the body. False
Explanation:
1. It is false because, although is true that a hematoma occurs when you have a large blood vessel damaged, i
t is a closed injury, not an open one.
2. It is true, you should never remove an avulsion skin flap, regardless of its size. The avulsion may have a serious infection.
3. It is false because ALS providers should administer IV fluid before the crushing object is lifted off the body.
If a person is "sterile", this means that they cannot reproduce. The word "sterilized" is essentially stating that there is no productive activity in order to be able to reproduce.
