The venom of a poison dart frog has the special ability of being quiet permeable through the skin. A dart frog's poison can travel up the nerves, into the brain leading from tingling to pain, to paralysis, to coma, and then death. Its agonising.
During freezing. Freezing is a type of fossilization in which everything is preserved. An example would be finding a woolly mammoth frozen in a glacier.
From what I remember it's called a substrate