Explain why an enzyme can no longer function once it has been denatured

1 answer:

7 0

All enzymes are proteinaceous in nature, hence there must be a structural organisation of the protein molecule. The specific structure of the protein of the enzymes is important for the activity of an enzyme.Therefore, once an enzyme structure is destroyed due to any condition such as temperature, pressure or salinity, the enzyme become no longer functional. The active site of an enzyme become lost due to denaturation, hence unable to bind with the substrate molecule for its activity.

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The transition state is the transition from substrate to product. The molecule is no longer a substrate but also not yet a product.

The enzyme is able to speed up the reaction by stabilizing the transition state. The transition state's energy is also the activation energy in terms of reaction. The activation energy is the minimum energy that is required to break some bonds of the reactants in order to turn them to products.

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