1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
dangina [55]
3 years ago
14

1. A mutant form of LDH in which Arg109 is replaced with Gln shows only 5% of the pyruvate binding and 0.07% of the activity of

wild-type enzyme. Provide a plausible explanation for the effects of this mutation.
Biology
1 answer:
Alex787 [66]3 years ago
4 0

Answer:

It is a replacement that has an important effect on protein function because Arg and Gln are residues with different chemical properties.

Explanation:

In this case, Arginine (Arg) is a basic and positively charged residue, while Glutamine (Gln) is an uncharged (neutral) amino acid. Non-conservative substitutions like that are generally expected to have deleterious effects and they are generally removed by natural selection. Moreover, Arg is also a target for phosphorylation, which is the most important posttranslational modification. Phosphorylation is known to be capable of causing the activation of different proteins, especially kinases, and, therefore, the mutation at Arg109 might also inactivate the active site of this protein.

You might be interested in
Researchers determine that the biodiversity in a woodland region is declining. They identify two major threats to the region's b
Mashutka [201]

The correct answer is: C. Reforestation would take the longest time to be effective because trees take several years to grow.

Reforestation is a process of re-growing trees in an area which had for some reason lost its forest cover (deforestation). This method is often used in order to rebuild natural habitats and ecosystems. Reforestation would benefit many species in a woodland region and biodiversity will increase.

8 0
4 years ago
Read 2 more answers
List 3 similarities that all 3 domains of life share
solong [7]

Answer:

The 3 similarities for the 3 domains (archaea, bacteria, and eukarya) of life share are <u>cellular organisation, biochemistry, and molecular biology</u>.

Explanation:

8 0
4 years ago
Compare ralph's treatment of the littluns with jack's. in chapters 5 - 6
spayn [35]
Ralph is being very compatible with the littluns unlike Jack who is being rough with them.
4 0
3 years ago
1. What does CDE stand for?
Solnce55 [7]

Answer:

A

Explanation:

Have a nICE DaY

5 0
4 years ago
During replication,<br>are responsible for joining the nucleotides of a new DNA strand together.​
Arte-miy333 [17]

Answer:

DNA ligase is responsible for this.

Explanation:

but the nucleotides are joined with sugars and ligase stitches them together.

6 0
4 years ago
Other questions:
  • Answer the following questions
    9·1 answer
  • Why do some cells have more mitochondria than other
    6·1 answer
  • Which molecular formula corresponds to this model of a chemical compound? (black = carbon; red = oxygen; white = hydrogen) A bal
    7·1 answer
  • What color of light most likely be present at 200 meters below sea level, an why
    15·1 answer
  • Researchers studying a small milkweed population note that some plants produce a toxin and other plants do not. They identify th
    10·1 answer
  • What is the use of protist in biological research?​
    10·1 answer
  • When the diaphragm contracts, _______. A. it lifts the rib cage B. it flattens out C. it flattens out and D. it rises in the tho
    13·2 answers
  • What are the 3 types of plate boundaries? Describe each.
    5·1 answer
  • 6) Compare the Wavelength, frequency, and energy of Red and Orange light
    8·1 answer
  • Over time, the hull of a sunken ship may become colonized by a wide range of marine organisms. What term is used to describe all
    11·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!