Yes, it is true that Mammalian target of rapamycin pathway mutations cause hemimegalencephaly and focal cortical dysplasia.
Focal malformations of cortical development, including focal cortical dysplasia (FCD) and hemimegalencephaly (HME), are important causes of intractable childhood epilepsy.
Using targeted and exome sequencing on DNA from resected brain samples and non-brain samples from 53 patients with FCD or HME, we identified pathogenic germline and mosaic mutations in multiple PI3K/AKT pathway genes in 9 patients, and a likely pathogenic variant in 1 additional patient.
Our data confirm the association of DEPDC5 with sporadic FCD but also implicate this gene for the first time in HME. Our findings suggest that modulation of the mammalian target of rapamycin pathway may hold promise for malformation-associated epilepsy.
Learn more about mutations here : brainly.com/question/17031191
#SPJ4
At a celebratory dinner for a recent publication, a marine biologist ordered the lobster claw appetizer. She ordered Cheliped.
<h3>What is Cheliped?</h3>
The chelipeds are the large claws that the crayfish uses for defense and to capture prey. Each of the four remaining segments contains a pair of walking legs. In the abdomen, the first five segments each have a pair of swimmerets, which create water currents and function in reproduction.
It is of the pair of legs that bears the large chelae in decapod crustaceans. It is a very delicious and nutricious food item. Some people are allergic but max people has no problem with this Cheliped .
From the above discussion we can conclude that at that celebratory dinner for a recent publication, that marine biologist ordered the Cheliped of lobster claw appetizer.
To know more about the lobster claw please click here : brainly.com/question/10006169
#SPJ4
Nitrogen fixation is a process in which nitrogen (N2) in the Earth's atmosphere is converted into ammonia (NH3). Atmospheric nitrogen or molecular dinitrogen (N2) is relatively inert: it does not easily react with other chemicals to form new compounds.
<span>A. endoskeleton
</span>Endoskeleton is not a characteristic of Arthropods that has attributed to their diversity and success. Endoskeleton is defined as inner characteristics of the skeletal feature of an organisms such as bears, humans, fish and etc.
Exoskeleton on the other hand is the trait by which arthropods posses. It is skeletal feature that is described outside or is extrinsic, this is evident as crabs have their skeletons outside of their body.
Answer: They are carbon, hydrogen, nitrogen, oxygen, phosphorus, and potassium.
Explanation: This is what surronds us and what that there is in plants is not as differnt from us if you think about it.
