Question

In electron micrographs of HSV infection, it can be seen that the intact virus initially reacts with cell surface proteoglycans, then with specific receptors. This is later followed by viral capsids docking with nuclear pores. Afterward, the capsids go from being full to being "empty." Which of the following best fits these observations? A) The viral envelope mediates entry into the cell, the capsid mediates entry into the nuclear membrane, and the genome is all that enters the nucleus. B) Only the genetic material of the virus is involved in the cell's infectivity, and is injected like the genome of a phage. C) The viral capsid mediates entry into the cell, and only the genomic DNA enters the nucleus, where it may or may not replicate. D) The viral envelope is not required for infectivity, since the envelope does not enter the nucleus.

Answer 1

Answer is option "A"

Explanation:

• The standards of nucleocytoplasmic transport, and afterward portray the various systems utilized by infections to convey their genomes into the host core. A portion of the developing instruments include:  
• An atomic section during mitosis, when the atomic envelope is dismantled
• Viral genome discharge in the cytoplasm followed by a passage of the genome through the atomic pore complex (NPC)
• Capsid docking at the cytoplasmic side of the NPC, trailed by genome discharge
• Atomic section of unblemished capsids through the NPC trailed by genome discharge
• Atomic passage by means of infection initiated disturbance of the atomic envelope. Which system a specific infection utilizes relies upon the size and structure of the infection  just as the cell signs utilized by the infection to trigger capsid dismantling and genome discharge  
• Hence, the right answer is option "A"