Assuming that the affection is a recessive trait caused by a single diallelic gene, the percentage of the population that possess the heter0zyg0us advantage is 32%.
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Available data</h3>
- 1000 of African people population
- 4% of the population is born with sickle cell anemia
100% of the population -------------------- 1000 individuals
4% of the population with anemia------- X = (4 x 1000) / 100 = 40
0.04 is the frequency of individuals with sickle cell anemia.
Assuming that the affection is a recessive trait caused by a single diallelic gene, we can get the allelic frequency as follows.
- The genotypic frequency is q² = 0.04
- The allelic frequency is q = √0.04 = 0.2
Having the recessive allelic frequency, we can get the dominant allelic frequency, by clearing the following equation,
p + q = 1
p = 1 - q
p = 1 - 0.2
p = 0.8
So, the allelic frequencies are
p = 0.8
q = 0.2
To get the heter0zyg0us frequency, we just need to replace the values
2pq = 2 x p x q = 2 x 0.2 x 0.8 = 0.32
The frequency of the heter0zyg0us genotype is 0.32 = 32%.
32% of the population possess the heterozygous advantage.
You can learn more about Hardy-Weinberg equilibrium at
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Answer:
You did not write the concept, so i will try to answer in a general way.
Why sometimes we really need to model concepts?
Well, sometimes the things are really complicated, or we just do not have the knowledge or tools to fully understand them.
Here is where the models came to be handy, we can somewhat "simplify" the things, and explain them with models.
For example, the movement of a particle as the wind pushes it can be really complex, so this can only be explained with a model.
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So for example, we could model how a given therapy acts on a given disease, and with that model, we could extrapolate the effects of the therapy in a similar disease (for example, testing how radiotherapy acts on a given tumor in some organ, can give information on how the same therapy can act on other types of tumors)
Concluding, models simplify some concepts, which allow us to understand them and work better with them