Keratinocytes are differentiated skin cells found in the outermost layer of the epidermis. Dendritic cells are antigen-presenting cells that play important roles in the adaptive immune response.
- In addition to keratinocytes, the <em>stratum spinosum</em> also contains another epidermal cell type called epidermal DENDRITIC cells that help to fight infection.
- The s<em>tratum spinosum</em><em> </em>is an epidermal skin layer between the <em>stratum granulosum </em>and<em> stratum basale</em>.
- Dendritic cells are antigen-presenting cells that are capable of processing harmful antigens in order to present them on the cell surface to the T cells of the immune system.
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Activation energy ........
Answer:
Bridgham et al. (2006) showed that the interaction between a steroid hormone (aldosterone-M) and its receptor (mineralocorticoid) evolved by Darwinian gradualism. In this work, the authors demonstrated a primitive affinity between the hormone and its receptor that was initially present in chemically similar but more ancient ligands. This result has implications in understanding the association between gene duplication and the evolution of hormone signaling pathways. For example, in invertebrates, this work reinforces the importance of gene duplication in the existing interaction between paralogous glucocorticoid receptors and their receptor mineralocorticoid genes that were derived from duplication (Thornton 2001).
The publications above cited are the following:
J.T. Bridgham, S.M. Carroll, and J.W. Thornton (2006). Evolution of hormone-receptor complexity by molecular exploitation. Science, 312(5770), 97-101.
JW Thornton. Evolution of vertebrate steroid receptors from an ancestral estrogen receptor by ligand exploitation and serial genome expansions, Proc Natl Acad Sci USA (PNAS), 2001, vol. 98 10 (pg. 5671-5676).
Bacteria, archaea, plants, protists, animals, and fungi, can use cellular respiration.
And the main ones that use celluar respiration are autotrophs and heterotrophs.
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