I don't know gosh!!!!!!!!!!!!!
Answer:
The correct answer is option d.
Explanation:
The non-genotoxic carcinogens lead to cancer not by amending the genotype, that is, they do not cause mutations straightforwardly. In spite, they result in cancers due to secondary mechanisms that are not associated with direct damage of the gene. They influence either the growth factors or the hormones related to growth.
The active site is complementary to its substrate due to its specific 3D structure. The substrate fits in to one specific active site so an enzyme will only bind to one substrate. They are SPECIFIC. Lock and key theory.