Background- In patients with intracranial artery stenosis, a long-term advantage of dual antiplatelet therapy (DAPT) over single antiplatelet therapy (SAPT) for the prevention of recurrent stroke has not been proven. We studied patients with intracranial arterial stenosis who were enrolled in the Cilostazol Stroke Prevention Study for Antiplatelet Combination trial, a randomized controlled trial in high-risk Japanese patients with ischemic stroke, to compare the efficacy and safety of DAPT with cilostazol and clopidogrel or aspirin to those of SAPT with clopidogrel or aspirin. Techniques and Outcomes In patients with ischemic stroke with symptomatic or asymptomatic intracranial arterial stenosis of at least 50% in a major intracranial artery, we compared the vascular and hemorrhagic events between DAPT and SAPT.
Patients were divided into two groups: 275 were given DAPT, while 272 were given SAPT. In contrast to SAPT, which had a higher risk of serious or life-threatening bleeding, DAPT had a lower risk of ischemic stroke (hazard ratio [HR], 0.47; 95% CI, 0.23-0.95); and a composite of stroke, myocardial infarction, and vascular mortality (HR, 0.48; 95% CI, 0.26-0.91). Conclusions In patients with intracranial artery stenosis following stroke, DAPT using cilostazol was superior than SAPT using clopidogrel or aspirin for the prevention of recurrent stroke and vascular events without raising bleeding risk.
<h3>What is
stroke?</h3>
When anything prevents blood flow to a portion of the brain or when a blood artery in the brain bursts, a stroke, also known as a brain attack, happens. The brain either ages or suffers harm in both scenarios. A stroke may result in permanent brain damage, chronic disability, or even fatality.
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Answer:
True
Explanation:
This is due to immigration
When you have a runny nose, "brain fluid leaking" typically isn't the first thing that comes to mind.
<h3>Why does CSF flow out of my nose?</h3>
The skull bone injury causes CSF to seep through the nose. Drainage of clear, watery fluid through one or both sides of the nose is the most typical sign of a CSF leak. When bending forward, tilting the head, or straining, this leaking can get worse.
<h3>Why is clear fluid dripping from my nose?</h3>
Allergies and illnesses like the common cold and influenza are the most frequent causes of clear liquid pouring from the nose. Another cause of a persistent runny nose is vasomotor rhinitis, in which there is no obvious reason why the condition exists. A leaking nose can be caused by nasal polyps, migraines, foreign bodies, and, very rarely, certain tumors.
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Answer:
Yes, a subtle one.
Explanation:
Symptoms of a panic attack are intense and disruptive. They often involve a sense of “unreality” and detachment. Anxiety symptoms vary in intensity, from mild to severe. Panic attacks appear suddenly, while anxiety symptoms become gradually more intense over minutes, hours, or days.
...
Now here's my take on it ( I have severe anxiety).
While Anxiety attacks take time to build up, panic attacks come out of nowhere (one moment you're fine, the next you can't breathe)
Comparing patients with CP to a community-based reference population, they have significantly lower QOL. Constant pain, opioid-based pain management, and alcohol aetiology are all independently linked to lower QOL. These variables only partially account for QOL, hence other variables must be found.
<h3>What is Chronic pancreatitis ?</h3>
Chronic inflammation causes the ducts to scar and fibrose, which damages several structures permanently and impairs the secretory processes. A pancreatic inflammatory condition that worsens over time and compromises both of the organ's functions called chronic pancreatitis.
- Chronic pancreatitis cannot be cured, but the associated pain and symptoms can be controlled or even avoided. Since drinking is the main cause of chronic pancreatitis, refraining from alcohol is frequently one strategy to lessen the discomfort.
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