Question

An example of epistasis is pigmentation in mice. The wild-type coat color, agouti (AA), is dominant to solid- colored fur (aa). However, a separate gene (C) is necessary for pigment production. A mouse with a recessive c allele at this locus is unable to produce pigment and is albino regardless of the allele present at locus A. 3. List all possible genotypes that would result in albino coloration.

Answer 1

Answer:

AAcc, Aacc, and aacc

Explanation:

Wild-type coat color, agouti (AA) is dominant over solid color fur (aa).

Gene C is needed for pigmentation, otherwise, the result is albinism.

Possible genotype for agouti color: AAC_ or AaC_

Possible genotype for solid color: aaC_

Recall that in order for the genotype to be an albino, gene C needs to be absent.

Hence, possible genotypes that would result in albinism: AAcc, Aacc, aacc