When you eat a apple your eating the hypanthium tissue it could also be the core but i dont know anyone who enjoys eating the core.
ANSWER: The origin of the pain is from the intervertebral disks of the lumbosacral spine.
EXPLANATION:
Sciatica is pain in the lower extremity resulting from irritation of the sciatic nerve.
The sciatic nerve is the largest nerve in the body and begins from nerve roots in the lumbar spinal cord in the low back and extends through the buttock area to send nerve endings down the lower limb.
Sciatica is caused by irritation of the root(s) of the lower lumbar and lumbosacral spine. Additional common causes of sciatica include: Lumbar spinal stenosis (narrowing of the spinal canal in the lower back) Degenerative disc disease (breakdown of discs, which act as cushions between the vertebrae).
A possible Hypothesis probably .
It is known as the opening statement
With chromosomes crossing over frequently, it's more likely that genetic defects will occur in offsprinfg.