Different enzymes have specific active sites which can only catalyze one <span>substrate. Enzyme-substrate complexes are produced only when the substrate fits into the active site :)</span>
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If Lorenzo would quit smoking,reduce his intake of alcohol and improve his healthy eating behaviors and also increasing his physical activity it would mean his lifestyle changes would then increase telomerase activity. Increase telomerase is one way of the body to deal with stress and for the protection of DNA from destruction.