Answer:
Abstract
Background and purpose: The sodium channel is a primary target for treating central nervous system disorders such as epilepsy. In this study the anticonvulsant effect of BmK IT2, a sodium channel-specific neurotoxin, was evaluated in different animal models of epilepsy.
Experimental approach: Experiments were performed on freely moving rats made epileptic by administration of either pentylenetetrazole (PTZ) or pilocarpine. BmK IT2 (0.05–0.5 μg in 2 μl) was microinjected into the CA1 area and its effects on PTZ-induced widespread, seizure-like behaviour and cortex epileptiform EEG, as well as on pilocarpine-induced seizure-like behaviour and c-Fos expression were studied.
Key results: Intrahippocampal application of BmK IT2 dose-dependently inhibited PTZ-induced seizure-like behaviour, and reduced the numbers and duration of the high amplitude and frequency discharges (HAFDs) of the epileptiform EEG component induced by PTZ. Similarly, in the pilocarpine-induced status epilepticus (SE) model, BmK IT2 significantly prolonged the latency to onset of the SE, reduced the severity of SE and suppressed hippocampal c-Fos expression during SE.
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Answer:
<h2>amiga pero dame corona te lo ruego de rodillas o igo am no se</h2>
Explanation:
Answer:pathos
Explanation:
Pathos is using ways that appeal to the aundience's emotions by using techniques that you know will eventually evoke the emotions that they already have about certain issues.
It is usually useful when one want to persuade a certain audience about a particular topic
When you tell people about let suffering and in addition show them the pictures , this automatically evoke feeling of empathy and strong emotions towards wanting to do something to change that , this will work for the activists to find more people who support his ideas on the matter.
Explanation:
no i don't play cod..........(-_-)
Explanation:
1) Identify common topic categories for informative speeches.
2) Identify strategies for researching and supporting informative speeches.
3) Explain the different methods of informing.
4) Employ strategies for effective informative speaking, including avoiding persuasion, avoiding information overload, and engaging the audience