The correct answers are: The lipid bilayer and proteins exist side by side without covalent bonds between them and Some proteins and lipids undergo lateral diffusion along the inner or outer surface of the membrane
According to fluid mosaic model, there is a lipid bilayer that gives fluidity and in which the protein molecules are embedded.
The membrane is mosaic because there is a pattern of different types of molecules that are put together. Molecules are constantly moving in two dimensions.
Components of the cell membrane include:
• Phospholipids – Form a bilayer
• Cholesterol –improves stability and reduce fluidity
• Proteins –integral (transmembrane) or peripheral
• Sugars-usually attached to proteins.
Stereotactic radiosurgery (SRS) and immune checkpoint inhibitors (ICI) are increasingly used to treat brain metastases, however there is a paucity of prospective data on the effectiveness of these treatments in terms of cancer control.
Data from patients treated with SRS for non-small cell lung cancer (NSCLC) and melanoma brain metastases at a single facility from May 2008 to January 2017 were retrospectively examined. The impact of concurrent ICI within 30, 60, or 90 days of ICI administration on local control and remote in-brain control is examined using a parametric proportional hazard model. The regression model takes into account other patient and lesion characteristics as covariates and makes adjustments.
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The restriction endonuclease EcoRI cleaves the DNA sequence 5'-GAATTC-3' in such a way as to leave a 5' overhang, which is often referred to as a "sticky end". To 5' overhang with the complementary sequence this sticky end adhere.
- The palindrome EcoRI restriction site breaks DNA after G and creates sticky ends with AATT. G/corresponding AATTC's DNA sequence is CTTAA/G, where "/" designates the location of the peptide bond break.
- When the ssDNA sequence 5'-GAATTC'-3 is recognised by the restriction endonuclease EcoRI, a single-strand cut is made between the G and A nucleotides.
- At the ultimate end of double-stranded DNA, an overhang is single-stranded DNA. This can occur on either strand, and if it does, there will either be a 5' overhang on the 5' end of the strand or a 3' overhang on the 3' end of the strand.
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Answer: Examples of beneficial mutations are HIV resistance, lactose tolerance, and trichromatic vision.
