Systemic lupus erythematosus (SLE) is a rheumatic disease attributed to autoimmune mechanisms.
Systemic lupus erythematosus (SLE, lupus) is characterized by a global loss of self-tolerance with activation of autoreactive T and B cells, leading to the production of pathogen autoantibodies and tissue damage.
Innate immune mechanisms are required for aberrant adaptive immune responses in SLE. Recent advances in basic and clinical biology have shed new light on the disease mechanisms of lupus. This review article describes recent studies that provide valuable insights into disease-specific therapeutic targets.
Systemic lupus erythematosus (SLE or lupus) is a systemic autoimmune disease with inflammation of multiple organs. SLE is characterized by the production of pathogenic autoantibodies against nucleic acids and their binding proteins, reflecting a global loss of self-tolerance.
Loss of tolerance with subsequent immune dysregulation is the result of genetic factors in the context of environmental triggers and stochastic events, with recent studies implicating more than 30 genetic loci in disease pathogenesis.
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Answer:
5. : Produces the body's major metabolic hormones.
Explanation:
The endocrine system is made up of several glands. The main ones are pituitary, thyroid, adrenal, pancreas, ovaries and testes. They secrete the body's main hormones, which are carried by the blood throughout the body, under the command of the nervous system, and act on specific cells. This, in turn, is formed by the central nervous system (CNS), the peripheral nervous system (PNS) and the autonomic nervous system (ANS). The basic units are nerve cells, which transmit electrical impulses accurately and quickly.
Thus, we can state that the production of the body's major metabolic hormones represents the way the nervous and endocrine systems work together.
The answer is A college course
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