Answer:
A. The chromatin near cis-regulatory sequences will be more closed and there will be less transcription.
Explanation:
In the presence of histones, the cis-regulatory sequences of DNA like promoter, enhancers etc. are not exposed. The function of the histone acetyltransferases (HATS) is to cause chromosome decondensation i.e. removal of histones from the DNA so that transcription of the DNA could occur. Histone acetyltransferases (HATS) cause acetylation of lysine amino acid of the histone proteins. Acetyl group is negatively charged so the acetylation of histone proteins leads to the removal of their positive charge which ultimately leads to the decrease in the interaction between N terminal of histones and negatively charged phosphate group of the DNA molecule. As soon as histones are removed from the DNA where cis-regulatory sequences are located, the DNA becomes accessible for transcription.
But here a drug has been added which blocks the activity of histone acetyltransferases (HATS) in cancer cells. So it is quite evident that in these cells, histones will not get removed from the cis-regulatory sequences of DNA so the DNA will be more closer or tightly packed as a result of which less transcription will occur.
Answer:
The sites of replication.
Explanation:
Linear DNA is and advantage for bigger organisms because there can be many places where replication can occur, otherwise, in circular DNA replication can only happen in he ORI place, that is unique. This feature allows to replicate several genes in the same amount of time being more efficient in protein synthesis.
The answer is: Cellular respiration is important because it provides the energy for living organisms to perform all of the other necessary functions to maintain life.
Answer:
Explanation:
The nucleus is surrounded by a membrane called the nuclear envelope, which protects the DNA and separates the nucleus from the rest of the cell.
Well, the mitochondria is the powerhouse of the cell, this cell would die off because it needs a mitochondria to work.