Autoantibodies that contribute to the destruction of beta cells contributes to the development of type I diabetes mellitus (DM)
Explanation:
The autoantibodies produced in the cells of the islet of Langerhans in the pancreas are the main contributors of type I diabetes mellitus, which is an autoimmune-mediated disease.
DM type I is caused due to inhibition of insulin secretion by the beta cells of the pancreas. The autoantibodies are produced due to the presence of autoantigens like GAD65 which causes autoimmune pathogenesis of the pancreatic beta cells.
Along with these autoantibodies, the T-cell receptors act as mediators in the destruction of beta cells which finally results in DM.
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This substance is produced in the liver, flows into small intestine, where it breaks down fat. nutrients are then absorbed through the wall of the small intestine.
the fat-soluble vitamins enter the vessels before making their way into the bloodstream.
C. arterial plaque deposition
C. drugs
D. more HDL