See a doctor as soon as possible
Individuals should participate in Aerobic exercises to increase cardiovascular endurance. (There's more exercises than just running that can increase your cardiovascular endurance, aerobic is more of a group of activities that do such)
Endocrine system regulates hormone production, Estrogen is one of the hormones
Estrogen regulates women's reproductive cycle. Also plays role in keeping bones strong n healthy. After menopause estrogen levels dramatically falls and women experience bone loss and osteoporosis. So, women population affected the greatest.
PS. Women start out life with less bone density then men already.