Answer:
The correct answer is - option A
Explanation:
Phosphoinositide 3-kinases or PI-3 kinse, are enzymes involved in essential cellular functions such as the growth of the cell, proliferation, motility, differentiation, survival and intracellular movement, which in turn are plays role in cancer.
PI3-kinase with oncogene PIK3CA and tumor suppressor PTEN, is implicated in the insensitivity of cancer tumors.
Thus, the correct answer is option A)
