Answer: Addison disease is an adrenal insufficiency. This occurs because of the fact that adrenal gland produces very low quantity of hormones like cortisol, and aldosterone.
Explanation:
1. The symptoms of addison disease are loss of appetite, increased thirst, low mood, and muscle fatigue.
2. The addison disease is an autoimmune reaction, which can affect people of all age groups.
3. It can cause other diseases like tuberculosis.
4. The hormone replacement therapy is ideal for the treatment for addison disease. The use of oral corticosteroids is ideal. The diet containing balanced proteins, carbohydrates, fats, increased intake of vegetables including vitamins, and minerals are necessary for treatment of addison disease.
Benzopyrene. Is the correct answer
A mutation which occurs when a base is introduced into the DNA sequence before transcription begins will lead to frame-shift of a single base on the DNA sequence resulting in nonfunctional protein from the transcribed mRNA.
Explanation:
This change either through addition or deletion of a single base in the codon sequences of the DNA will modify the amino acid codes and will result in nonfunctional proteins after transcription.
This mutation will just result in change of a single base, i.e., it would be added either to the enhancer region or the silencer region of the sequence before the promoter which initiates transcription.
The mRNA produced due to mutated DNA sequence after the deletion or insertion point will be read as out of frame thus resulting in nonsense protein.
There are so many examples for that in different areas, like biology experiment carried out in our lab recently.
Here's one link : https://www.creative-biogene.com/Services/Biosimilar-Cell-Line-Development.html
