The hypothesis by Coleman was that the product of the ob+ gene was the appetite suppressing hormone. Hence, the homozygous ob/ob mutant are in a position to synthesize that hormone, and its circulating level would be zero. He also hypothesized that the product of the db+ gene was the receptor for the appetite-suppressing hormone. Thus, the homozygous db/db mutant would be able to synthesize the hormone but would not be in a position to respond to it. It would eat excessively and produce large amounts of body fat, which in turn would produce large amounts of appetite-suppressing hormone . In the absence of a receptor, the db/db mutant's hormone level would remain abnormally high.
Coleman's hypothesis were confirmed when the precise functions of the ob+ and db+ genes were determined. The peptide hormone encoded by the ob+ gene was named Leptin.
Answer:
Incomplete Dominance
Explanation:
In terms of the shape of the blood cell shape, sickle cell disease has an incomplete dominance.
Answer:
RNA polymerase is the main transcription enzyme. Transcription begins when RNA polymerase binds to a promoter sequence near the beginning of a gene (directly or through helper proteins). RNA polymerase uses one of the DNA strands (the template strand) as a template to make a new, complementary RNA molecule.
Explanation:
please mark me as brainliest
Answer;
Gold
Gold is a non renewable resource.
Explanation;
Non renewable resources are those resources of economic value that can not be readily replaced by natural means on a level that is equivalent to its consumption.
Examples of non renewable resources include; fossil fuels such as oil, natural gas and coal; because their source is not sustainable.
