Question

What is 2x3x6x4x7x5x0x4x5

Answer 1

I followed the numbers across, thinking to myself "this won't be
too hard to multiply, because they're all small numbers".  And then
when I got to the zero, I burst out laughing !  It doesn't matter at all
what all the other numbers are.  Once there's a zero in there, the whole
product will be zero, no matter what else gets multiplied along the way.
There could be millions and billions in there.  You wouldn't need to do
any calculating at all.  With zero as a factor, you know right away that
the product is zero.

Answer 2

So your question is 
$\sf{2\times3\times6\times4\times7\times5\times}$ $\bf{0}$ $\sf{\times4\times5=}$

We need to use this property:
$\sf{a \times 0=0}$

So then your problem has one number that is a 0. And all these numbers are getting multiplied. That means you could have like a million numbers, but if you multiply it by 0 even once, your final answer will be 0.

So your final answer is 

$\boxed{\bf{0}}$