The first sign of syphilis is a small sore, called a chancre (SHANG-kur). The sore appears at the spot where the bacteria entered your body. While most people infected with syphilis develop only one chancre, some people develop several of them. The chancre usually develops about three weeks after
There are four stages of the disease: primary, secondary, latent, and tertiary (also known as neurosyphilis). Primary syphilis is the first stage of the disease. It causes one or more small, painless sores in or around the genitals, anus, or mouth.
Sores appear in the genital (penis or vagina) area or the mouth within 10 days to 3 months after infection.The sores are usually firm, round, small, and painless.The sores should go away on their own, but bacteria stays in the body (without treatment).
In women of childbearing age, folic acid supplementation has a demonstrable and meaningful benefit, reducing the incidence of NTDs. Its use in this population is evidence-based and demonstrably effective
